Publications

Pharmacokinetic comparison of lutein and zeaxanthin in granule, beadlet and liposomal powder formulations following single oral administration in male Sprague-Dawley rats

S. Mehkri, K.G. Dinesh, G. Ashok, Krathish Bopanna

Current Functional Foods · doi:10.2174/0126668629434731250915053757

Tissue pharmacokinetics of lipid-based berberine formulations: relevance to hepatic and intestinal exposure

Krathish Bopanna

Annals of Pharmacology and Pharmaceutical Sciences · doi:10.52338/apps.2026.5950 · Preprint: doi:10.20944/preprints202606.1187.v1

Curcumin–thymoquinone complex (CTQ) in mitochondrial resilience and inflammasome regulation: a translational review

Krathish Bopanna

The European Journal of Cancer · doi:10.52338/tejoc.2025.5238

Comparative pharmacokinetics of lutein and zeaxanthin from phospholipid, liposomal and MCT formulations in SD rats

S. Mehkri, K.G. Dinesh, G. Ashok, Krathish Bopanna

Pharmaceutics 17(12):1552 · doi:10.3390/pharmaceutics17121552

Phosphatidylserine matrix enhances lutein/zeaxanthin exposure versus phosphatidylcholine, liposome and MCT oil in rats: a 24-hour pharmacokinetic study

S. Mehkri, K.G. Dinesh, G. Ashok, Krathish Bopanna

Preprints.org · doi:10.20944/preprints202510.1830.v1

Comparative pharmacokinetics of different coenzyme Q₁₀ formulations in Wistar rats: superior bioavailability of phospholipid complex and lipid-encapsulated delivery systems

S. Mehkri, K.G. Dinesh, G. Ashok, Krathish Bopanna

World Journal of Advanced Research and Reviews 27(3):789–801 · doi:10.30574/wjarr.2025.27.3.3214

Pharmacokinetics of micronized and water-dispersible palmitoylethanolamide in comparison with standard palmitoylethanolamide following single oral administration in male Sprague-Dawley rats

Indian Journal of Pharmacology · doi:10.4103/IJP.IJP_964_24

Enhanced and synergistic inhibition of pro-inflammatory cytokines (IL-1β, IL-17A and IL-6) by a curcumin–thymoquinone complex (CurQnone®), compared to curcumin monotherapy, in LPS-stimulated RAW 264.7 murine macrophages

S. Mehkri, K.G. Dinesh, G. Ashok, Krathish Bopanna

World Journal of Pharmaceutical Science and Research · doi:10.5281/zenodo.17130164

Anti-inflammatory effects of a curcumin–thymoquinone complex (CurQnone®) and curcumin alone in LPS-stimulated RAW 264.7 cells: a comparative study

S. Mehkri, K.G. Dinesh, G. Ashok, Krathish Bopanna

International Journal of Pharmaceutical Sciences · doi:10.5281/zenodo.15735101

Natural mixed carotenoid complex (CaroRite™) on macular pigment optical density (MPOD) and central foveal thickness (CFT): a randomised, double-blind, placebo-controlled study

International Journal of Medical and Health Research · View article

The effects of lutein and zeaxanthin (Lute-gen®) supplementation, with and without natural mixed carotenoids, on central foveal thickness and its relationship with macular pigment optical density in healthy adult subjects: a randomized, double-blind, placebo-controlled study

S. Mehkri, M.B. Thirumalesh, M.V. Krishnaiah, G. Ashok, Krathish Bopanna

International Journal of Ophthalmology Research 5(1) · doi:10.33545/26181495.2023.v5.i1a.23

The key role of vitamin C and zinc in throat health and the benefits of regular fortified lozenge use in counteracting discomfort

International Journal of Medical and Health Research · View article

The effects of lutein and zeaxanthin (Lute-gen®) supplementation, with and without natural mixed carotenoids, on macular pigment optical density in healthy adult subjects: a randomized, double-blind, placebo-controlled study

S. Mehkri, M.B. Thirumalesh, M.V. Krishnaiah, G. Ashok, Krathish Bopanna

International Journal of Ophthalmology Research 4(1) · doi:10.33545/26181495.2022.v4.i1a.21

Evaluation of Thymopure™ (Nigella sativa) oil on the in vitro expression levels of selected cytokines in mouse macrophage cells

International Journal of Biology Research · View article

Evaluation of in vitro immunomodulatory activity of Thymopure™ Nigella sativa oil in dendritic cells

S. Mehkri, K. Chandrasagar, G. Ashok, Krathish Bopanna

International Journal of Biology Research · View article

Evaluation of in vitro phagocytic property of macrophages in presence of Thymopure™ (Nigella sativa) oil

S. Mehkri, K. Chandrasagar, G. Ashok, Krathish Bopanna

International Journal of Biology Research · View article

Effect of two doses of fenugreek flakes (FenuLean™) on appetite, body weight and blood glucose homeostasis: a randomized, double-blind, multicenter, three-arm, long-term, controlled study in 100 healthy subjects

S. Mehkri, C. Ambarish, B.J. Madankumar, Preethi Shivayogi, Krathish Bopanna

International Journal of Medical and Health Research · doi:10.13140/RG.2.2.14684.24962

Assessment of onset, duration, sleep efficiency and quality of sleep through SleepRite™ combination product(s) on adult subjects with difficulties in falling asleep

N. Shobha, Sampath, Preethi Shivayogi, Jaishankar, Krathish Bopanna

International Journal of Medical and Health Research · View article

Effect of lutein (Lute-gen®) on proliferation rate and telomere length in vitro and possible mechanism of action

International Journal of Biology Research · View article

Effect of fenugreek fiber flakes on appetite scores and glucose homeostasis in healthy subjects

International Journal of Medical and Health Research · View article

Perspective and challenges in conducting ophthalmology studies in India

Krathish Bopanna

View record

Managing clinical trials in India

Krathish Bopanna, Jayanti Gupta

Pharmaceutical Medicine · doi:10.1007/BF03256755

Organotropic ultrastructural changes produced by monosodium glutamate in rats on atherogenic diet: effect of S-allyl cysteine sulphoxide

K.N. Bopanna, R. Balaraman, R.S. Nadig

Indian Journal of Pharmacology 31(4):266–274 · View abstract

Role of S-allyl cysteine sulphoxide in antagonising deleterious metabolic effects of monosodium glutamate in rats on atherogenic diet

K.N. Bopanna, R. Balaraman, R.S. Nadig

Indian Journal of Pharmacology 30(3):152–162 · View abstract

Antioxidant status of S-allyl cysteine sulphoxide on monosodium glutamate potentiated atherogenesis

K.N. Bopanna, R. Balaraman, R.S. Nadig

Indian Journal of Pharmacology 30(2):73–81 · View abstract

Antidiabetic and antihyperlipaemic effects of neem seed kernel powder on alloxan diabetic rabbits

Indian Journal of Pharmacology 29(3) · View abstract

Cell culture derived Hemidesmus indicus in the prevention of hypercholesterolemia in normal and hyperlipidemic rats

K.N. Bopanna, N. Bhagyalakshmi, S.P. Rathod, R. Balaraman, J. Kannan

Indian Journal of Pharmacology 29(2):105–109 · View abstract